Recombinant Human TNFRSF1A
A member of the TNFR superfamily, it is one of the major receptors for tumor necrosis factor-alpha (TNFα). Binding of either TNF-α or TNF-β to TNFRSF1A starts a signal transduction pathway that results in the activation of the transduction factor NF-κB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis.
Product Specifications
Gene Name
TNFRSF1A
Gene Aliases
Soluble Tumor Necrosis Factor Type I, TNFRSF1A, TNFAR, TNF-R55, TNFR60, p55, CD120a
Gene ID
7132
Accession Number
P19438
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Molecular Weight
18.4
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
coming soon
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