Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Biotinylated Human Nectin-4 Protein, His, Avitag™ (MALS verified)

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

Product Specifications

Background

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

Specifications

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 37.8 kDa. The protein migrates as 40-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q96NY8-1

Expression Region

Gly 32 - Ser 349

Host

HEK293

Target

Nectin-4

Conjugation

Biotin-labeled

Tag

C-10xHis & C-Avi

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Enfortumab at 1 μg/mL (100 μL/well) can bind Biotinylated Human Nectin-4, His,Avitag (Cat. No. NE4-H82E7) with a linear range of 0.06-2 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

37.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

25ug*1

Host or Source

HEK293

Species

Human

Protein ID

Q96NY8-1

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PLA2G3, CT (PLA2G3, Group 3 secretory phospholipase A2, Group III secretory phospholipase A2, Phosphatidylcholine 2-acylhydrolase 3) (FITC) discontinued
040116-FITC 200 µL

PLA2G3, CT (PLA2G3, Group 3 secretory phospholipase A2, Group III secretory phospholipase A2, Phosphatidylcholine 2-acylhydrolase 3) (FITC) discontinued

Ask
View Details
pEnCMV-MAP4K4-3×FLAG-SV40-Neo Plasmid
PVT39866 2 µg

pEnCMV-MAP4K4-3×FLAG-SV40-Neo Plasmid

Ask
View Details
p16INK4A (CDKN2A) (NM_000077) Human Mass Spec Standard
PH320937 10 µg

p16INK4A (CDKN2A) (NM_000077) Human Mass Spec Standard

Ask
View Details
DTX-P7
HY-P10757 1 Each

DTX-P7

Ask
View Details
Rabbit Polyclonal GBP6 Antibody [Janelia Fluor 549]
NBP2-81719JF549 0.1 mL

Rabbit Polyclonal GBP6 Antibody [Janelia Fluor 549]

Ask
View Details