Biotinylated Human CEACAM-5 / CD66e (499-685) Protein, His, Avitag™ (MALS verified)

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 23.6 kDa. The protein migrates as 43-58 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P06731-1

Expression Region

Glu 499 - Ala 685

Host

HEK293

Target

CEACAM-5

Conjugation

Biotin-labeled

Tag

C-10xHis & C-Avi

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Anti-CEACAM-5 (labetuzumab) Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Biotinylated Human CEACAM-5 (499-685) Protein, His,Avitag (Cat. No. CE5-H82E3) with a linear range of 0.06-1 ng/mL (QC tested).