JNJ-42253432

Product Specifications

CAS Number

1428327-35-8

Target

P2X Receptor

Related Pathways

Neuroscience|||Membrane transporter/Ion channel

Purity

0.9998

Bioactivity

JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.

Smiles

CN1CCc2c(C1)cccc2C(=O)NCC1(CCCCC1)N1CCN(CC1)c1ccccc1

Molecular Formula

C28H38N4O

Molecular Weight

446.63

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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