Anti-PAR14 PARP14 Antibody
Boster Bio Anti-PAR14 PARP14 Antibody catalog # A06171. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Poly [ADP-ribose] polymerase 14; PARP-14;2.4.2.30
Gene Name
PARP14
UniProt
Q460N5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Tissue Specificity
Expressed in macrophages.
Applications
WB, ELISA
Purification
PAR14 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
ADP-ribosyltransferase (PubMed:16061477, PubMed:27796300) . By mono-ADP-ribosylating STAT1 at 'Glu-657' and 'Glu-705' and thus decreasing STAT1 phosphorylation, negatively regulates pro-inflammatory cytokines production in macrophages in response to IFNG stimulation (PubMed:27796300) . Mono-ADP- ribosylates STAT6 (By similarity) . Enhances STAT6-dependent transcription (By similarity) . In macrophages, positively regulates MRC1 expression in response to IL4 stimulation by promoting STAT6 phosphorylation (PubMed:27796300) . Mono-ADP- ribosylates PARP9 (PubMed:27796300) .
Molecular Weight
202800 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Poly [ADP-ribose] polymerase 14
Subcellular Location
Nucleus
Protein Name
Poly [ADP-ribose] polymerase 14
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