RS 09 (TFA)
Product Specifications
UNSPSC Description
RS 09 TFA is a TLR4 agonist. RS 09 TFA promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 TFA acts as an adjuvant in vivo; RS 09 TFA enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.
Target Antigen
Toll-like Receptor (TLR)
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rs-09-tfa.html
Purity
99.81
Solubility
DMSO : ≥ 100 mg/mL|H2O : ≥ 50 mg/mL
Smiles
OC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C([C@@H]2CCCN2C([C@@H](N)C)=O)=O)=O)CC3=CNC=N3)=O)C)=O)CC(C)C)=O)CO)=O.O=C(O)C(F)(F)F
Molecular Weight
805.80
References & Citations
[1]Arulkumaran Shanmugam,et al. Synthetic Toll Like receptor-4 (TLR-4) Agonist Peptides as a Novel Class of Adjuvants. PLoS One. 2012;7(2):e30839.Int Immunopharmacol. 2024 May 9:134:112188.|Phytomedicine. 28 July 2022, 154360.|Bioact Mater. 2022 Nov 9;23:69-79.|Bioact Mater. 2023, 23: 69-79.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1439A/RS-09-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1439A/RS-09-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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