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PMX-53 TFA

PMX-53 is a potent C5a receptor antagonist (IC50 = 0.3 μM) that inhibits C5a-induced MPO release in human PMNs in vitro. It demonstrates in vivo efficacy by reducing inflammation in rat Arthus reaction and Huntington's disease models, and attenuates atherosclerosis in ApoE-/- mice.

Product Specifications

Field of Research

Immunology & Inflammation; Stem Cell & Developmental Biology

Molecular Weight

896.09

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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