Recombinant Murine Interleukin-22

Product Specifications

Product Name Alternative

IL-TIF, IL-TIF alpha, IL-22a

UniProt

Q9JJY9

Source

Escherichia coli

Field of Research

Immunology & Inflammation

Endotoxin

Less than 1 EU/ug of rMuIL-22 as determined by LAL method.

Purity

> 96 % by SDS-PAGE and HPLC analyses.

Bioactivity

Fully biologically active when compared to standard. The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.2 ng/ml, corresponding to a specific activity of > 5.0 x106 IU/mg.

Form

Lyophilized from a 0.2 μm filtered concentrated solution in 1 x PBS, pH 7.4.

Molecular Weight

Approximately 16.6 kDa, a single non-glycosylated polypeptide chain containing 146 amino acids.

Storage Conditions

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Notes

For research use only.

AA Sequence

LPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV SAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV