SC-2001
SC-2001 is a compound structurally related to obatoclax that has better antitumor effects than obatoclax in liver cancer cell lines, downregulating Mcl-1 protein levels, inhibiting STAT3 phosphorylation, inducing apoptosis, and enhancing SHP1 expression and activity.
Product Specifications
CAS Number
[1383727-17-0]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sc-2001.html
Concentration
10mM
Purity
99.37
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(/C=C2N=CC=C/2)NC(C(N3)=CC4=C3C=CC(Br)=C4)=C1
Molecular Formula
C18H14BrN3O
Molecular Weight
368.23
References & Citations
[1]A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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