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Setmelanotide

Setmelanotide is a potent and selective MC4R agonist (EC50 ~0.27 nM) used to investigate obesity, metabolic disorders, and neuroendocrine pathways. Its applications include in vitro studies of receptor signaling and inflammation, as well as in vivo research on energy homeostasis, drug-induced weight gain, and blood pressure modulation.

Product Specifications

Product Name Alternative

BIM 22493, BIM22493, BIM-22493, IRC 022493, IRC022493, IRC-022493, hMC1R, hMC3R, hMC4R, hMC5R, MelanocortinReceptor, Melanocortin Receptor, RM 493, rMC4R, RM493, RM-493, Setmelanotide

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.93% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (2.95 mM) ; DMSO:100 mg/mL (89.5 mM) ; H2O:50 mg/mL (44.75 mM)

Molecular Weight

1117.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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