Recombinant Human DTD1 Protein (His Tag)
Product Specifications
Background
D-tyrosyl-tRNA (Tyr) deacylase 1 (DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA (Tyr) into D-tyrosine and free tRNA (Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.
Abbreviation
DTD1
Synonyms
C20orf88; D-tyrosyl-tRNA (Tyr) deacylase 1; DNA-unwinding element-binding protein B; DTD1; DUE-B; DUEB; HARS2; Histidyl-tRNA synthase-related
UniProt
Q8TEA8
Accession Number
Q8TEA8
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Pro209
Field of Research
Signal Transduction; epigenetics and nuclear signal; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
24.5 kDa
Observed Molecular Weight
30 kDa
Formulation
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Species
Human
Available Sizes
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