Recombinant Human TNF-α Protein (Gst Tag)

Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1, CD120a, p55/60) and TNF-R2 (TNF receptor type 2, CD120b, p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1) . TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.

Tumor Necrosis Factor Ligand Superfamily Member; TNFSF; TNF; DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F; TNF alpha; Cachectin; Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; APC1; APC1 protein; DIF、TNF-alpha、TNFA、TNFSF2; Differentiation inducing factor; Macrophage cytotoxic factor; macrophage derived; member 2; Membrane Form; monocyte derived; soluble form; sTNFA; TNF superfamily; Tumor necrosis factor alpha

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.