Recombinant Human Bridging Integrator 2/BIN2 Protein (His Tag)
Product Specifications
Background
Bridging Integrator 2 (BIN2) is a cytoplasmic protein. BIN2 contains one BAR domain and Interacts with BIN1. BIN2 is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. BIN2 is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling. Genetic studies show that BIN2 is inhibited in response to BR perception at the cell surface to relieve its inhibitory effects on downstream targets.
Abbreviation
Bridging Integrator 2; BIN2
Synonyms
BIN2; BRAP1; Breast Cancer-Associated Protein 1; Bridging Integrator 2
UniProt
Q9UBW5
Accession Number
Q9UBW5
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Asn244
Field of Research
Cell biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
30.6 kDa
Observed Molecular Weight
32 kDa
Species
Human
Available Sizes
Documents
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