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Recombinant c Met Monoclonal Antibody

Product Specifications

Background

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Abbreviation

C Met

UniProt

P08581

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human Met (c-Met)

Target

MET; AUTS9; DFNB97; HGFR; RCCP2; c-Met

Clonality

Monoclonal

Clone

R02-4D6

Conjugation

Unconjugated

Applications

WB; IHC-P; IF

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Signal Transduction

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:1000-1:2000; IHC 1:20-1:50; IF 1:20-1:200

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

156kDa

Observed Molecular Weight

170kDa

Isotype

IgG

Available Sizes

Curated Selection

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