THG1L Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA (His) . Several transcript variants encoding different isoforms have been found for this gene.
Abbreviation
THG1L
UniProt
Q9NWX6
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human THG1L
Target
ICF45; Interphase cytoplasmic foci protein 45; Probable tRNA (His) guanylyltransferase; THG1; THG1L; tRNA histidine guanylyltransferase 1 like (S. cerevisiae) ; tRNA-histidine guanylyltransferase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology
Purification
Antigen affinity purification
Concentration
0.9 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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