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BAG3 Polyclonal Antibody

Product Specifications

Background

Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

Abbreviation

BAG3

UniProt

O95817

Host

Rabbit

Reactivity

Human; Rat

Immunogen

Recombinant Human BAG3 protein expressed by E.coli

Target

BAG family molecular chaperone regulator 3 ; BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BIS

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Cell Biology; Metabolism

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

62 kDa

Observed Molecular Weight

80 kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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