EIF4A1 Monoclonal Antibody
Product Specifications
Background
EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Abbreviation
EIF4A1
UniProt
P60842
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide
Target
ATP-dependent RNA helicase eIF4A-1; DDX2; DDX2A; eIF 4A I; eIF-4A-I; EIF4A; eIF4A I; eIF4A-I; EIF4A1; Eukaryotic initiation factor 4A-I; Eukaryotic initiation factor 4AI; eukaryotic translation initiation factor 4A; isoform 1; Eukaryotic translation initiation factor 4A1; IF4A1
Clonality
Monoclonal
Clone
Clone:2B6
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:3000; IHC 1:50-1:300; IF 1:100-1:200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/uqmal8
Product MSDS
https://789.bio/eb/eXLmL8
Observed Molecular Weight
48kDa
Isotype
IgG
Available Sizes
Curated Selection
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