MUC1 Recombinant Rabbit Monoclonal Antibody [SN06-80]

Mucin 1, cell surface associated (MUC1), also called polymorphic epithelial mucin (PEM) or epithelial membrane antigen or EMA, is a mucin encoded by the MUC1 gene in humans. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

ADMCKD antibody ADMCKD1 antibody Breast carcinoma associated antigen DF3 antibody Breast carcinoma-associated antigen DF3 antibody CA 15-3 antibody CA15 3 antibody CA15 3 antigen antibody CA15.3 antibody Cancer antigen 15-3 antibody Carcinoma associated mucin antibody Carcinoma-associated mucin antibody CD 227 antibody CD227 antibody DF3 antigen antibody EMA antibody Episialin antibody H23 antigen antibody H23AG antibody KL 6 antibody KL-6 antibody KL6 antibody Krebs von den Lungen-6 antibody MAM 6 antibody MAM6 antibody MCD antibody MCKD antibody MCKD1 antibody Medullary cystic kidney disease 1 (autosomal dominant) antibody Medullary cystic kidney disease, autosomal dominant antibody MUC 1 antibody MUC-1 antibody MUC-1/SEC antibody MUC-1/X antibody MUC1 antibody MUC1-alpha antibody MUC1-beta antibody MUC1-CT antibody MUC1-NT antibody MUC1/ZD antibody MUC1_HUMAN antibody Mucin 1 antibody Mucin 1 transmembrane antibody Mucin 1, cell surface associated antibody Mucin-1 subunit beta antibody Peanut reactive urinary mucin antibody Peanut-reactive urinary mucin antibody PEM antibody PEMT antibody Polymorphic epithelial mucin antibody PUM antibody Tumor associated epithelial membrane antigen antibody Tumor associated epithelial mucin antibody Tumor associated mucin antibody Tumor-associated epithelial membrane antigen antibody Tumor-associated mucin antibody

Abbreviation

MUC-1, CA 15-3, KL-6, PUM, PEM, EMA, MUC1

Swiss Prot

P15941 Human, Q02496 Mouse,

Cellular Locus

Apical cell membrane, Secreted, Cell membrane, Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human MUC1 aa 1,206-1,255 / 1,255.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IP

Positive Control

HeLa cell lysate, T-47D cell lysate, mouse lung tissue lysate, rat lung tissue lysate, HeLa, B16F1, human lung carcinoma, human endometrial carcinoma, human kidney tissue.