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GNAT1 Polyclonal Antibody

Product Specifications

Background

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.GNAT1 (G Protein Subunit Alpha Transducin 1) is a Protein Coding gene. Diseases associated with GNAT1 include Night Blindness, Congenital Stationary, Autosomal Dominant 3 and Night Blindness, Congenital Stationary, Type 1G. Among its related pathways are Phospholipase-C Pathway and Phototransduction. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GNAT2.

Abbreviation

GNAT1

UniProt

P11488

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human GNAT1

Target

CSNBAD3; GBT1; GNAT1; GNAT1; GNATR; guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1; guanine nucleotide binding protein G (T) alpha 1 subunit; Guanine nucleotide-binding protein G (t) subunit alpha-1; Rod specific transducin; rod-type transducin alpha subunit; Transducin alpha-1 chain; transducin; rod-specific

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Neuroscience; Signal Transduction

Purification

Antigen affinity purification

Concentration

0.66 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

40 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Frequently Asked Questions

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