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Anti-Vitamin D Binding protein/Gc Antibody Picoband®

Boster Bio Anti-Vitamin D Binding protein/Gc Antibody Picoband® catalog # A03364-2. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Vitamin D-binding protein, also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene.The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues.

Synonyms

Vitamin D-binding protein; DBP; VDB; Gc-globulin; Group-specific component; Gc

Gene Name

Gc

Gene ID

14473

UniProt

P21614

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived mouse Gc recombinant protein (Position: L17-E256) .

Clonality

Polyclonal

Applications

ELISA, WB

Field of Research

Actin Binding Proteins, Actin, etc., Cancer, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction, Tumor Antigens, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.

References & Citations

1. Mikkelsen M, Jacobsen P, Henningsen K (Jul 1977) . Possible localization of Gc-System on chromosome 4. Loss of long arm 4 material associated with father-child incompatibility within the Gc-System. Hum Hered. 27 (2) : 105–7. 2. Yamamoto N, Suyama H, Yamamoto N (2008) . Immunotherapy for Prostate Cancer with GcProtein-Derived Macrophage-Activating Factor, GcMAF ([PDF]) . TRANSLATIONAL ONCOLOGY. 1 (2) : 65–72.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

53 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Group specific component

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

243

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