ECE2 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.
Abbreviation
ECE2
UniProt
O60344
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human ECE2
Target
ECE 2; ECE-2; ECE2; ECE2; Endothelin converting enzyme 2; Endothelin-converting enzyme 2 region; Hypothetical protein MGC2408; KIAA0604; MGC17664; MGC78487
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cardiovascular; Neuroscience; Signal transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-2000; IHC 1:30-150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
100 kDa
Isotype
IgG
Available Sizes
Curated Selection
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