Anticancer agent 177
Product Specifications
UNSPSC Description
Anticancer agent 177 (Compound 11b) is a NAMPT inhibitor and DNA alkylating agent. Anticancer agent 177 has antitumor activity in vitro and in vivo[1].
Target Antigen
DNA Alkylator/Crosslinker; NAMPT
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-177.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC(N(CCCl)CCCl)=C1)N2CCC(CC2)CCCCNC(/C=C/C3=CN=CC=C3)=O
Molecular Weight
531.52
References & Citations
[1]Fu Y, et al. Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion. J Med Chem. 2023 Dec 7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161051/Anticancer-agent-177-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161051/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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