NBN Polyclonal Antibody
Product Specifications
Background
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Abbreviation
NBN
UniProt
O60934
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human NBN
Target
AT V1; AT V2; ATV; Cell cycle regulatory protein p95; FLJ10155; MGC87362; Nbn; NBN; NBS 1; NBS; NBS1; Nibrin; Nijmegen breakage syndrome 1 (nibrin) ; Nijmegen breakage syndrome; Nijmegen breakage syndrome protein 1; p95; p95 protein of the MRE11/RAD50 complex
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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