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PARP11 Polyclonal Antibody

Product Specifications

Background

Poly (ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly (ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly (ADPribose) chains on the protein.

Abbreviation

PARP11

UniProt

Q9NR21

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human PARP11

Target

5330431N24Rik; AI851877; C12orf6; DKFZp779H0122; HIN1L; MIB006; OTTMUSP00000027219; Poly (ADP ribose) polymerase family member 11; RGD1561791

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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