GC-IN-2

GC-IN-2 (Compound 25) is a potent, selective, and nonsugar glucocerebrosidase inhibitor with an IC50 of 6.46 μM. GC-IN-2 can be utilized in research related to Gaucher disease[1].

Product Specifications

CAS Number

[333441-43-3]

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/gc-in-2.html

Smiles

O=C(NC1=CC=CC=C1)C2=CC=C(NS(=O)(C3=CC=CC=C3)=O)C=C2

Molecular Formula

C19H16N2O3S

Molecular Weight

352.41

References & Citations

[1]Zheng W, et al. Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. Proc Natl Acad Sci U S A. 2007 Aug 7;104 (32) :13192-7.