Cereblon inhibitor 1

Cereblon inhibitor 1, an isoindoline derivative, is a cereblon E3 ubiquitin ligase modulating agent. Cereblon inhibitor 1 has the potential for cancer research.

Product Specifications

CAS Number

[2672489-14-2]

UNSPSC

12352208

Hazard Statement

H302-H315-H319-H335

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cereblon-inhibitor-1.html

Purity

99.19

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CC1=CC=C(N2CCN(CC3=CC=C(COC4=CC=CC5=C4CN([C@@H](CC6)C(NC6=O)=O)C5=O)C(F)=C3)CC2)C(F)=C1Cl

Molecular Formula

C32H28ClF2N5O4

Molecular Weight

620.05

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hui Liu, et al. Isoindoline derivative and its application. WO2021147889A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Available Sizes

Curated Selection

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