F-SAHA
F-SAHA is a HDAC inhibitor (HDACi) and its 18F labeled derivative can be used in tumor imaging research[1].
Product Specifications
CAS Number
[149648-08-8]
Product Name Alternative
P-Fluoro-SAHA
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/f-saha.html
Concentration
10mM
Purity
99.90
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
O=C(CCCCCCC(NC1=CC=C(C=C1)F)=O)NO
Molecular Formula
C14H19FN2O3
Molecular Weight
282.31
References & Citations
[1]Hendricks JA, et al. In vivo PET imaging of histone deacetylases by 18F-suberoylanilide hydroxamic acid (18F-SAHA) . J Med Chem. 2011 Aug 11;54 (15) :5576-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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