Gly-Pro-pNA (Hydrochloride)

<strong>Gly-Pro-pNA (Hydrochloride)</strong>_x000D_ <strong>Catalog number:</strong> B2013109_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 328.8 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Gly-Pro p-nitroanilide, GP-pNA_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kim YB, Kopcho LM, Kirby MS, Hamann LG, Weigelt CA, Metzler WJ, Marcinkeviciene J. Mechanism of Gly-Pro-pNA cleavage catalyzed by dipeptidyl peptidase-IV and its inhibition by saxagliptin (BMS-477118) Arch Biochem Biophys. 2006 Jan 1;445(1):9-18._x000D_ 2: Divya K, Vivek HK, Priya BS, Nanjunda Swamy S. Rapid detection of DPP-IV activity in porcine serum: A fluorospectrometric assay Anal Biochem. 2020 Mar 1;592:113557._x000D_ 3: Mäkinen PL, Mäkinen KK, Syed SA. An endo-acting proline-specific oligopeptidase from Treponema denticola ATCC 35405: evidence of hydrolysis of human bioactive peptides Infect Immun. 1994 Nov;62(11):4938-47._x000D_ 4: Yoshimoto T, Tsuru D. Proline-specific dipeptidyl aminopeptidase from Flavobacterium meningosepticum J Biochem. 1982 Jun;91(6):1899-906._x000D_ 5: Bauvois B. Murine thymocytes possess specific cell surface-associated exoaminopeptidase activities: preferential expression by immature CD4-CD8- subpopulation Eur J Immunol. 1990 Mar;20(3):459-68._x000D_ 6: Shibuya-Saruta H, Sugiyama M, Kasahara Y. Colorimetrical rate assay for urinary dipeptidyl peptidase IV (DPPIV) activity using a new substrate J Clin Lab Anal. 1995;9(2):113-8._x000D_ 7: Nandan AS, Nampoothiri KM. Unveiling aminopeptidase P from Streptomyces lavendulae: molecular cloning, expression and biochemical characterization Enzyme Microb Technol. 2014 Feb 5;55:7-13._x000D_ 8: Blanco J, Jacotot E, Callebaut C, Krust B, Hovanessian AG. Further characterization of DPP IV-beta, a novel cell surface expressed protein with dipeptidyl peptidase activity Adv Exp Med Biol. 1997;421:193-9._x000D_ 9: Fu P, Sun W, Lai J, Shen YH, Zhang Z. Identification of two isoforms of Pop in the domestic silkworm, Bombyx mori: Cloning, characterization and expression analysis Gene. 2018 Aug 15;667:101-111._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/11883961">10: Hinke SA, Kühn-Wache K, Hoffmann T, Pederson RA, McIntosh CH, Demuth HU. Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1 Biochem Biophys Res Commun. 2002 Mar 15;291(5):1302-8. </a>_x000D_ _x000D_ <strong>Products Related to Gly-Pro-pNA (Hydrochloride) can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>