AZD 4017
AZD 4017 is a potent, selective 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) inhibitor, with an IC50 of 7 nM.
Product Specifications
CAS Number
1024033-43-9
UNSPSC
12352005
Hazard Statement
H302
Target
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/AZD_4017.html
Purity
99.20
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)C[C@H]1CN(C2=NC(SCCC)=C(C(NC3CCCCC3)=O)C=C2)CCC1
Molecular Formula
C22H33N3O3S
Molecular Weight
419.58
Precautions
H302
References & Citations
[1]Scott JS, et al. Discovery of a potent, selective, and orally bioavailable acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor: discovery of 2-[ (3S) -1-[5- (cyclohexylcarbamoyl) -6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid (AZD4017) . J Med Chem. 2012 Jun 28;55 (12) :5951-64.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2F3]](https://cdn.genprice.uk/products/937/6868c3d9994c49e6dc400b5e/imageurl/ta808335am.webp)
TA808335AM 100 µL
Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2F3]
Sign In for Pricing
View Details 
BNC882478-100 1x 100 µL
CD3e (T-Cell Marker) (C3e/2478), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
KN401345 1 Kit
DOPA Decarboxylase (DDC) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
