Recombinant Human ST6GALNAC2 Protein (His Tag)
Product Specifications
Background
Alpha-N-Acetylgalactosaminide α-2,6-Sialyltransferase 2 (ST6GALNAC2) belongs to the glycosyltransferase 29 family that adds sialic acids to the non-reducing ends of glycoconjugates. At the cell surface, these modifications play roles in cell-cell and cell-substrate interactions, bacterial adhesion and protein targeting. ST6GALNAC2 is localized to the Golgi apparatus membrane. ST6GALNAC2 is highly expressed in lactating mammary glands and the adult testis; it is expressed at lower levels in the kidney. ST6GALNAC2 can catalyze 2,6-sialylation of the Tn antigen.
Abbreviation
ST6GALNAC2
Synonyms
6-Sialyltransferase 2;6-Sialyltransferase II; Alpha-N-Acetylgalactosaminide Alpha-2; GalNAc Alpha-2; SIAT7-B; SIAT7B; SIATL1; ST6GALNAC2; ST6GalNAc II; ST6GalNAcII; STHM; SThM; Sialyltransferase 7B
UniProt
Q9UJ37
Accession Number
Q9UJ37
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ser29-Arg374
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
38.8 kDa
Observed Molecular Weight
44 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, 5% Trehalosen, pH 7.4.
Species
Human
Available Sizes
Documents
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