Recombinant Human ST6GALNAC2 Protein (His Tag)

Product Specifications

Background

Alpha-N-Acetylgalactosaminide α-2,6-Sialyltransferase 2 (ST6GALNAC2) belongs to the glycosyltransferase 29 family that adds sialic acids to the non-reducing ends of glycoconjugates. At the cell surface, these modifications play roles in cell-cell and cell-substrate interactions, bacterial adhesion and protein targeting. ST6GALNAC2 is localized to the Golgi apparatus membrane. ST6GALNAC2 is highly expressed in lactating mammary glands and the adult testis; it is expressed at lower levels in the kidney. ST6GALNAC2 can catalyze 2,6-sialylation of the Tn antigen.

Abbreviation

ST6GALNAC2

Synonyms

6-Sialyltransferase 2;6-Sialyltransferase II; Alpha-N-Acetylgalactosaminide Alpha-2; GalNAc Alpha-2; SIAT7-B; SIAT7B; SIATL1; ST6GALNAC2; ST6GalNAc II; ST6GalNAcII; STHM; SThM; Sialyltransferase 7B

UniProt

Q9UJ37

Accession Number

Q9UJ37

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ser29-Arg374

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

38.8 kDa

Observed Molecular Weight

44 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, 5% Trehalosen, pH 7.4.

Species

Human

Available Sizes

Documents

Product Datasheet

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