2'-Deoxyadenosine-13C10
2'-Deoxyadenosine-13C10 is 13C-labeled 2'-Deoxyadenosine. 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer[2][3][4].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Caspase; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-deoxyadenosine-13c10.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
O[13C@H]1[13CH]([H])[13C@H](N2[13CH]=N[13C]3=[13C]2N=[13CH]N=[13C]3N)O[13C@@H]1[13CH2]O
Molecular Formula
13C10H13N5O3
Molecular Weight
261.17
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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