ABCG2 Mouse Monoclonal Antibody
Product Specifications
Background
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.
Product Name Alternative
MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; CDw338; EST157481; MGC102821
Gene Name
ABCG2
Gene ID
9429
Swiss Prot
Q9UNQ0
Host
Mouse
Reactivity
Human, Mouse, Monkey
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC, ELISA
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, ICC 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
72kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
