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Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7)

Selected Variant

HY-P990294-01

Size: 1 mg

Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) is an anti-mouse CD106/VCAM-1 IgG1 monoclonal antibody. Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) reduces inflammatory response and oxidative stress by lowering p-STAT3 and reactive oxygen species (ROS) levels. Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) can alleviate cardiac inflammation and fibrosis by reducing the expression of collagen I and collagen III. Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) can be used for research on cardiovascular conditions such as hypertensive heart condition and subretinal fibrosis[1][2][3].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Collagen; Interleukin Related; Reactive Oxygen Species (ROS) ; STAT; Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Cytoskeleton; Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd106-vcam-1-antibody-m-k-2-7.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCD106/VCAM-1Antibody(M/K-2.7)]

Molecular Weight

(150 kDa)

References & Citations

[1]Kelly KA, et al. Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle. Circ Res. 2005 Feb 18;96 (3) :327-36.|[2]Deng W, et al. Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions. Immun Ageing. 2023 Nov 20;20 (1) :65.|[3]Qiu ZY, et al. Blocking VCAM-1 ameliorates hypertensive cardiac remodeling by impeding macrophage infiltration. Front Pharmacol. 2022 Nov 17;13:1058268.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Isoform

Collagen I; Collagen III; IL-1; IL-6; STAT3

Available Sizes

Price

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