Picrasidine Q
Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity[1].
Product Specifications
CAS Number
[101219-61-8]
UNSPSC
12352005
Target
Apoptosis; FGFR
Type
Natural Products
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/picrasidine-q.html
Solubility
10 mM in DMSO
Smiles
O=C1C(OC)=C(C2=NC=CC3=C2N1C4=CC=CC=C34)O
Molecular Formula
C15H10N2O3
Molecular Weight
266.25
References & Citations
[1]Shi Y, et al. FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. J Cell Biochem. 2018;119 (2) :2231-2239.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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