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RC363

RC363 is a novel probucol analog with the activity to protect mouse hippocampal cells and primary cortical neurons from glutamate-induced oxidative cell death (ferroptosis) and increase glutathione peroxidase (GPx) 1 levels and activity.

Product Specifications

CAS Number

[2584411-86-7]

UNSPSC

12352005

Target

Glutathione Peroxidase

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rc363.html

Smiles

OC1=C(C(C)(C)C)C=C(SC2=CC=CS2)C=C1C(C)(C)C

Molecular Formula

C18H24OS2

Molecular Weight

320.51

References & Citations

[1]New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GPX1

Curated Selection

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