Equine IL-12/IL-23 p40 Recombinant Protein

The Equine IL-12/IL-23 p40 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Equine IL-12/IL-23 p40 applications are for cell culture, ELISA standard, and Western Blot Control. The Equine IL-12/IL-23 p40 yeast-derived recombinant protein can be purchased in multiple sizes. Equine IL-12/IL-23 p40 Specifications: (Molecular Weight: 34.9 kDa) (Amino Acid Sequence: IWELEKDVYV VELDWYPDAP GEMVVLTCNT PEEEGITWTS AQSNEVLGSG KTLTIQVKEF GDAGWYTCHK GGEVLSHSHL LLHKKEDGIW STDILKDQKE SKNKTFLKCE AKNYSGRFTC WWLTAISTDL KFSVKSSRGS SDPRGVTCGA ATLSAERVSV DDREYKKYTV ECLEGSACPA AEESLPIEIV VDAVHKLKYE NYTSGFFIRD IIKPDPPKNL QLKPLKNSRQ VEVSWEYPET WSTPHSYFSL TFSIQVQGKN KKERKDRLFM DETSATVTCH KDGQIRVQAR DRYYSSSWSE WASVSCS (307) ) (Gene ID: 100034222) . For research use only.

Product Specifications

Background

IL-12 is a member of the IL-12 family, which includes IL-12, IL-23, IL-27, and IL-35. Like other IL-12 family members, IL-12 is a heterodimeric cytokine. IL-12 is encoded by two separate genes, IL-12A (p35) and IL-12B (p40) . The active heterodimer, and a homodimer of p40 are formed following protein synthesis. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-γ and TNF-α from T and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ.