Neoline

Neoline (Bullatine B) is the active ingredient of the active ingredient (PA), which can be used to cure the disease. Neoline Flow Suppression Nav1.7 Electrical Flow Control (VGSC), improve diabetes mechanical pain sensitivity. Neoline has a list of compounds that can be used, research on its use, and the quality of its processing during processing in pain[1][2].

Product Specifications

CAS Number

[466-26-2]

Product Name Alternative

Bullatine B

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/neoline.html

Purity

98.0

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O[C@@H]1C23[C@@]4([H])[C@](COC)(CN(CC)C2C([C@]5(O)[C@]6([H])[C@@]3([H])C[C@@]([C@@H](OC)C5)([H])[C@@H]6O)[C@@H]4OC)CC1

Molecular Formula

C24H39NO6

Molecular Weight

437.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Tanimura Y, et al. Neoline is the active ingredient of processed aconite root against murine peripheral neuropathic pain model, and its pharmacokinetics in rats.J Ethnopharmacol. 2019 Sep 15;241:111859.|[2]Nakatani Y, Negoro K, Yamauchi M, et al. Neoline, an active ingredient of the processed aconite root in Goshajinkigan formulation, targets Nav1.7 to ameliorate mechanical hyperalgesia in diabetic mice. J Ethnopharmacol. 2020;259:112963.