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EA4

EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA. EA4 can inhibit rPLA2 with a Ki value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis[1].

Product Specifications

CAS Number

389614-94-2

UNSPSC

12352005

Target

Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ea4.html

Purity

98.75

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C(C1=CC=C(N(CC)CC)C=C1)=C2Cl)C3=C(N=CC=C3)C2=O

Molecular Formula

C19H17ClN2O2

Molecular Weight

340.80

References & Citations

[1]Shin, Hae Sook et al. Purification and characterization of a cytosolic, 42-kDa and Ca2+-dependent phospholipase A2 from bovine red blood cells: its involvement in Ca2+-dependent release of arachidonic acid from mammalian red blood cells. The Journal of biological chemistry vol. 277,23 (2002) : 21086-94.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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