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Dopamine D3 receptor ligand-6

Dopamine D3 receptor ligand-6 (Compound 196476) is a selective dopamine D3 receptor (D3) antagonist. Dopamine D3 receptor ligand-6 is promising for research of substance use disorders (such as opioid and psychostimulant addiction) [1].

Product Specifications

CAS Number

[687634-09-9]

UNSPSC

12352005

Target

Dopamine Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

COC1=C2C(C=C(C(NCCCCN3CCN(C4=C(Cl)C(Cl)=CC=C4)CC3)=O)O2)=CC=C1

Molecular Formula

C24H27Cl2N3O3

Molecular Weight

476.40

References & Citations

[1]Won SJ, et al. Decoding the Structure-Activity Relationship of the Dopamine D3 Receptor-Selective Ligands Using Machine and Deep Learning Approaches. J Chem Inf Model. 2025 Jun 9;65 (11) :5495-5507.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

D3 Receptor

Curated Selection

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