Eotaxin (CCL11) Antibody
Product Specifications
Background
Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-gamma-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
CAS Number
9007-83-4
NCBI Gene ID
6356
Swiss Prot
P51671
Accession Number
P51671
Host
Rabbit
Reactivity
Human
Immunogen
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hEotaxin. Anti-Human Eotaxin specific antibody was purified by affinity chromatography employing immobilized hEotaxin matrix.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Antibody Pairs
Field of Research
Chemokines & Cytokines, Immunology, Other
Purification
Eotaxin specific antibody was purified by affinity chromatography employing immobilized hEotaxin matrix
Concentration
Batch dependent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Symbol
CCL11
NCBI Official Name
C-C motif chemokine ligand 11
NCBI Organism
Homo sapiens
Other Product Names
CCL11
Tested Applications
ELISA, WB
Protein ID
P51671.1
Physical Properties
Lyophilized
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