Rab3ip (NM_001003950) Mouse Recombinant Protein
Product Specifications
Background
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
B230311A06; Gtpat12; Rabin3
Gene ID
216363
UniProt
Q68EF0, Q8BR32
Accession Number mRNA
NM_001003950
Chromosomal Location
10 64.96 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
47.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rab3ip
Species
Mouse
Protein ID
NP_001003950
Overview
Purified recombinant protein of Mouse RAB3A interacting protein (Rab3ip), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/216363
Uniprot URL
https://www.uniprot.org/uniprot/Q68EF0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001003950
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001003950
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