CCX-777
CCX-777 is a partial agonist of β-arrestin-2 recruitment to ACKR3 (atypical chemokine receptor 3) [1].
Product Specifications
CAS Number
1226686-36-7
UNSPSC
12352005
Target
Arrestin
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ccx-777.html
Concentration
10mM
Purity
98.73
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCCN1CCCC1)CC(N2CCN(C3=C4N=CC=CC4=CC=C3OC)CCC2)C5=CSC(N6CCOCC6)=N5
Molecular Formula
C31H43N7O3S
Molecular Weight
593.78
References & Citations
[1]Gustavsson M, et al. Structural basis of ligand interaction with atypical chemokine receptor 3. Nat Commun. 2017 Jan 18;8:14135.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
