What is the catalog number for 360A?

The catalog number for 360A is HY-15595.

What sizes are available for 360A?

360A is available in the following size(s): 1 mg, 5 mg.

How many pack sizes does 360A come in?

360A is available in 2 different pack sizes.

360A is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures 360A?

360A is manufactured by QuantiMol.

What is the estimated delivery time for 360A?

Estimated delivery time for 360A is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for 360A?

The safety data sheet for 360A is available here: http://file.medchemexpress.com/batch_PDF/HY-15595/.

360A

360A is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay.

Product Specifications

CAS Number

794458-56-3

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

G-quadruplex; Telomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/360a.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=CC(C(NC2=C[N+](C)=C3C=CC=CC3=C2)=O)=N1)NC4=C[N+](C)=C5C=CC=CC5=C4

Molecular Formula

C27H23N5O2

Molecular Weight

449.50

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Pennarun G, et al. Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands. Oncogene. 2005 Apr 21;24 (18) :2917-28.|[2]Gauthier LR, et al. Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death. Cell Mol Life Sci. 2012 Feb;69 (4) :629-40.