N4-Benzoyl-2’-O-methylcytidine

N4-Benzoyl-2’-O-methylcytidine is a natural cytidine nucleoside analog. Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420) ) and have potential antimetabolite and antitumor activities[1][2].

Product Specifications

CAS Number

[52571-45-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n4-benzoyl-2-o-methylcytidine.html

Purity

99.26

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O[C@H]1[C@@H](OC)[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@@H]1CO

Molecular Formula

C17H19N3O6

Molecular Weight

361.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3 (11) :1062-8.|[2]Increasing the viability or longevity of an organ or organ explant using modified mRNAs for proteins essential for organ survival. World Intellectual Property Organization, WO2013096709 A2 2013-06-27.