Heliosupine
Heliosupine is a pyrrolizidine alkaloid. Heliosupine is an acetylcholinesterase (AChE) inhibitor, with an IC50 0.57 mM. Heliosupine exhibits deterrent effects against generalist herbivores[1][2].
Product Specifications
CAS Number
32728-78-2
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/heliosupine.html
Solubility
10 mM in DMSO
Smiles
CC(C)(O)[C@]([C@@H](O)C)(O)C(OCC1=CCN2[C@@]1([H])[C@@H](OC(/C(C)=C\C)=O)CC2)=O
Molecular Formula
C20H31NO7
Molecular Weight
397.46
References & Citations
[1]Benamar H, et, al. Pyrrolizidine alkaloids from Solenanthus lanatus DC. with acetylcholinesterase inhibitory activity. Nat Prod Res. 2016 Nov;30 (22) :2567-2574.|[2]Dam NM, et, al. The "Raison D'être" of pyrrolizidine alkaloids in Cynoglossum officinale: Deterrent effects against generalist herbivores. J Chem Ecol. 1995 May;21 (5) :507-23.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE
Available Sizes
Frequently Asked Questions
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