Human CARD18 Protein

<strong>Human CARD18 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011695_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 500 µg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> pseudo-ICE protein, CARD-18, Caspase recruitment domain-containing protein 18 protein, ICEBERG protein, CARD18, CARD 18, CARD-18 protein, UNQ5804 protein, CARD 18 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Aral K, Berdeli E, Cooper PR, Milward MR, Kapila Y, Karadede Ünal B, Aral CA, Berdeli A. Differential expression of inflammasome regulatory transcripts in periodontal disease J Periodontol. 2020 May;91(5):606-616._x000D_ 2: Qin H, Jin J, Fischer H, Mildner M, Gschwandtner M, Mlitz V, Eckhart L, Tschachler E. The caspase-1 inhibitor CARD18 is specifically expressed during late differentiation of keratinocytes and its expression is lost in lichen planus J Dermatol Sci. 2017 Aug;87(2):176-182._x000D_ 3: Lu A, Li Y, Schmidt FI, Yin Q, Chen S, Fu TM, Tong AB, Ploegh HL, Mao Y, Wu H. Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism Nat Struct Mol Biol. 2016 May;23(5):416-25._x000D_ 4: Göblös A, Danis J, Vas K, Bata-Csörgő Z, Kemény L, Széll M. Keratinocytes express functional CARD18, a negative regulator of inflammasome activation, and its altered expression in psoriasis may contribute to disease pathogenesis Mol Immunol. 2016 May;73:10-8._x000D_ 5: Green DR, Melino G. ICE heats up Cell Death Differ. 2001 Jun;8(6):549-50._x000D_ 6: Mahakur S, Saikia B, Minz M, Minz RW, Nada R, Anand S, Sharma A, Jha V, Joshi N, Goel L, Arora A, Joshi K. Allo-specific immune response profiles indicative of acute rejection in kidney allografts using an in vitro lymphocyte culture-based model Clin Exp Nephrol. 2018 Apr;22(2):465-473._x000D_ 7: Tan C, Liu S, Xiang Z. [The expression of CARD18 in apoptin-transfected gastric cancer cells and gastric adenocarcinoma tissues] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2013 Aug;29(8):858-61._x000D_ 8: Wright CM, Savarimuthu Francis SM, Tan ME, Martins MU, Winterford C, Davidson MR, Duhig EE, Clarke BE, Hayward NK, Yang IA, Bowman RV, Fong KM. MS4A1 dysregulation in asbestos-related lung squamous cell carcinoma is due to CD20 stromal lymphocyte expression PLoS One. 2012;7(4):e34943._x000D_ 9: Johansson Å, Eriksson N, Becker RC, Storey RF, Himmelmann A, Hagström E, Varenhorst C, Axelsson T, Barratt BJ, James SK, Katus HA, Steg PG, Syvänen AC, Wallentin L, Siegbahn A; PLATO Investigators. NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO) Circ Cardiovasc Genet. 2015 Jun;8(3):498-506._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/18473111">10: da Cunha JP, Galante PA, de Souza SJ. Different evolutionary strategies for the origin of caspase-1 inhibitors J Mol Evol. 2008 Jun;66(6):591-7. </a>_x000D_ _x000D_ <strong>Products Related to Human CARD18 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>