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HOXD4 Antibody

Product Specifications

Background

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.

NCBI Gene ID

3233

Swiss Prot

P09016

Accession Number

P09016

Host

Rabbit

Reactivity

Human

Immunogen

This HOXD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the C-terminal region of human HOXD4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-503

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HOXD4

NCBI Official Name

Homeobox protein Hox-D4

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, H., et al. Acta Pharmacol. Sin. 31 (8) :977-983 (2010)

Background Reference 02

Ester, A.R., et al. Am. J. Med. Genet.149A (12), 2745-2752 (2009) :

Background Reference 03

Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

Background Reference 04

Tan, Y., et al. BMC Mol. Biol. 10, 12 (2009) :

Other Product Names

Homeobox protein Hox-D4, Homeobox protein HHOC13, Homeobox protein Hox-4B, Homeobox protein Hox-51, HOXD4, HOX4B

Tested Applications

WB

Protein ID

20141491

Physical Properties

Liquid

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