Sutimlimab
Sutimlimab is a humanized monoclonal IgG4 antibody. Sutimlimab inhibits complement protein component 1, s subcomponent (C1s) . Sutimlimab blocks C3 and C4 activation. Sutimlimab can be used for the research of cold agglutinin disease and complement-mediated hemolytic uremic syndrome[1][2][3].
Product Specifications
CAS Number
[2049079-64-1]
Product Name Alternative
BIVV009; IPN-009; TNT009
UNSPSC
12352203
Target
Complement System
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sutimlimab.html
Purity
98.81
Solubility
H2O
Smiles
[Sutimlimab]
Molecular Weight
(144.8 kDa)
References & Citations
[1]Alexander Röth, et al. Sutimlimab in Cold Agglutinin Disease. N Engl J Med. 2021 Apr 8;384 (14) :1323-1334.|[2]Cole MA, et al. Complement Biosensors Identify a Classical Pathway Stimulus in Complement-Mediated Hemolytic Uremic Syndrome. bioRxiv [Preprint]. 2024 Jun 2:2024.05.29.596475.|[3]Berentsen S. Sutimlimab for the Treatment of Cold Agglutinin Disease. Hemasphere. 2023 May 2;7 (5) :e879.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Available Sizes
Curated Selection
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