MMAF sodium
Product Specifications
CAS Number
1799706-65-2
Target
ABC Transporter, Microtubule Associated, ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related, Membrane transporter/Ion channel, Cytoskeletal Signaling
Bioactivity
MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumor agent.
Smiles
[H][C@@]1([C@@H]([C@H](C(N[C@H](C([O-])=O)Cc2ccccc2)=O)C)OC)CCCN1C(C[C@H]([C@@H](N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C)[C@H](CC)C)OC)=O.[Na+]
Molecular Formula
C39H64N5NaO8
Molecular Weight
753.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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