(S, R, S) -AHPC-Me-C6-NH2

(S, R, S) -AHPC-Me-C6-NH2 can be used for the synthesis of PROTAC[1]. (S, R, S) -AHPC-Me-C6-NH2 (Compound SI-9) contains VHL ligand 2 (HY-112078) [2].

Product Specifications

CAS Number

[2411422-49-4]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-me-c6-nh2.html

Purity

99.81

Solubility

DMSO : ≥ 100 mg/mL

Smiles

NCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O)=O

Molecular Formula

C30H45N5O4S

Molecular Weight

571.77

References & Citations

[1]Haibing Zhou, et al. Oseltamivir PROTAC compound, preparation method thereof and application thereof in anti-influenza virus drugs. Patent CN112592331A.|[2]Bondeson DP, et al. Systematic profiling of conditional degron tag technologies for target validation studies. Nat Commun. 2022 Sep 20;13 (1) :5495.